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Precise Staging in Cancer Surgery with Sentinel Lymph Node Biopsy (ICG)

What is a sentinel lymph node?

When cancer cells begin to spread, the first lymph node they reach is called the "sentinel lymph node." Evaluating this node plays a critical role in understanding the extent of the disease.

Traditional surgery involves the removal of numerous lymph nodes, whereas sentinel lymph node biopsy allows for the evaluation of only the target lymph node.

How to locate a sentinel lymph node using ICG (fluorescent dye)?

During the surgery, a special dye (ICG – indocyanine green) is applied to the cervix or related tissue.
This dye travels along the lymphatic channels and marks the sentinel lymph node.

With specialized camera systems:

  • Lymph flow is monitored in real time.

  • Sentinel nodes are detected with high accuracy.

  • Unnecessary extensive lymph node dissections are avoided.

Image of sentinel lymph node surgery in endometrial cancer.
ICG sentinel lenf nodu tarafından tutulmuş

In which patients is it used?

Sentinel lymph node biopsy specifically:

  • Endometrial (uterine) cancer

  • Cervical (uterine cervix) cancer

  • Early-stage gynecological cancers

It is preferred in suitable patients.

Patient selection is done individually based on tumor characteristics and stage.

What are the advantages?

Less surgical trauma
Instead of extensive lymph node removal, a targeted procedure is performed.

Lower risk of complications.
In particular, lymphedema and lymphatic complications decrease.

Faster recovery
Postoperative recovery time is shortened.

High diagnostic accuracy
With accurate staging, the treatment plan is determined more clearly.

Is it applicable to every patient?

No. Sentinel lymph node biopsy:

  • tumor type

  • phase

  • surgical plan

It is selected taking into consideration.

In some advanced or high-risk cases, classic lymph node dissection may be necessary.

How is the surgical approach planned?

A treatment plan is created individually for each patient.
Sentinel lymph node biopsy:

  • alone

  • or as part of extensive surgery

applicable.

© 2026 by Burak Tatar

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